Geludrox HS (200 mg+400 mg+30 mg)/5 ml

Geludrox HS (200 mg+400 mg+30 mg)/5 ml

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Medicine overview

Indications of Geludrox HS (200 mg+400 mg+30 mg)/5 ml

This is indicated for symptomatic relief of hyperacidity associated with the peptic ulcer, gastritis, peptic oesophagitis, gastric hyperacidity, heartburn, sour stomach or hiatus hernia. It is effective in the prevention of stress ulceration and GI bleeding. It acts as an antiflatulent to alleviate … Read moreThis is indicated for symptomatic relief of hyperacidity associated with the peptic ulcer, gastritis, peptic oesophagitis, gastric hyperacidity, heartburn, sour stomach or hiatus hernia. It is effective in the prevention of stress ulceration and GI bleeding. It acts as an antiflatulent to alleviate the symptoms of gas including post operative gas pain. This rapidly relieves acid pain, disperses gastric foam and facilitates eructation of gas and air.

Composition

Each tablet contains- Dried Aluminium Hydroxide Gel BP (Al2O3, 47% minimum): 425.53 mg Magnesium Hydroxide BP: 400 mg Simethicone USP: 30 mg Each 5 ml contains- Aluminium Oxide (Equivalent amount of Aluminium Hydroxide Gel USP): 200 mg Magnesium Hydroxide (Equivalent amount of Magnesium Hydroxide Paste USP): 400 mg Simethicone USP: 30 mg

Theropeutic Class

Antacids

Pharmacology

This is the mixture of non-systemic acid neutralizing substances and antiflatulent. This preparation offers reliability as well as long action. Aluminium Hydroxide and Magnesium Hydroxide induce the relief of ulcer by neutralizing gastric acid secreted from parietal cells of the stomach. The clinical use of simethicone is based on its antifoam properties. Simethicone spreads on the surface of aqueous liquids, forming a film of low surface tension and causing collapse of foam bubbles. Simethicone repeatedly allows mucous surrounded gas bubbles in the GI tract to coalesce and be expelled.This is used in the treatment of flatulence and meteorism for the elimination of gas, air or foam from the gastro-intestinal tract prior to radiography and for the relief of abdominal distension and dyspepsia. Simethicone is physiologically inert; it does not appeared to be absorbed from the GI tract to interfere with gastric secretion or absorption of nutrients. Following oral administration, the drug is excreted unchanged in the feces.

Dosage & Administration of Geludrox HS (200 mg+400 mg+30 mg)/5 ml

Tablet: 1-2 tablets 1-3 hours after meal and at bed time or as directed by the physician.Suspension: 1-2 teaspoonful 1-3 hours after meal and at bedtime or as directed by the physician.

Dosage of Geludrox HS (200 mg+400 mg+30 mg)/5 ml

Tablet: 1-2 tablets 1-3 hours after meal and at bed time or as directed by the physician.Suspension: 1-2 teaspoonful 1-3 hours after meal and at bedtime or as directed by the physician.

Interaction of Geludrox HS (200 mg+400 mg+30 mg)/5 ml

All antacids may increase or decrease the rate and/or extent of absorption of concomitantly administered oral drugs. Antacids decrease the bioavailability of theophyline, tetracycline, quinolone antibiotics, isoniazide, ketoconazole, ethambutol, some antimuscarinic drugs, benzodiazepines, phenothiazines, ranitidine, indomethacine, nitrofurantoin, fluoride, phosphate, propanolol, atenolol, digoxins, vitamins etc. Antacids increase the bioavailability of some drugs; e.g. sulphonamides, levodopa, valproic acid, enteric coated aspirin etc.

Contraindications

This should not be administered in patients with renal failure or hypophosphataemia or in those who are severely debilitated. It is also contraindicated in alkalosis and hypermagnesaemia, where abdominal distention may be due to partial or complete intestinal obstruction.

Side Effects of Geludrox HS (200 mg+400 mg+30 mg)/5 ml

Gastrointestinal side effects are uncommon. Occasionally, if excessive amount is consumed, diarrhea, constipation or regurgitation may occur.

Pregnancy & Lactation

It is advised to avoid antacid preparations in the first trimester of pregnancy.

Precautions & Warnings

This should be used with caution in patients with kidney disease.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Drug Classes

Antacids

Mode Of Action

This is the mixture of non-systemic acid neutralizing substances and antiflatulent. This preparation offers reliability as well as long action. Aluminium Hydroxide and Magnesium Hydroxide induce the relief of ulcer by neutralizing gastric acid secreted from parietal cells of the stomach. The clinical use of simethicone is based on its antifoam properties. Simethicone spreads on the surface of aqueous liquids, forming a film of low surface tension and causing collapse of foam bubbles. Simethicone repeatedly allows mucous surrounded gas bubbles in the GI tract to coalesce and be expelled.This is used in the treatment of flatulence and meteorism for the elimination of gas, air or foam from the gastro-intestinal tract prior to radiography and for the relief of abdominal distension and dyspepsia. Simethicone is physiologically inert; it does not appeared to be absorbed from the GI tract to interfere with gastric secretion or absorption of nutrients. Following oral administration, the drug is excreted unchanged in the feces.

Pregnancy

It is advised to avoid antacid preparations in the first trimester of pregnancy.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

Additional Information

Quantity

200 ml bottle

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