ORS 10.25 gm

ORS 10.25 gm

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Medicine overview

Indications of ORS 10.25 gm

Oral Rehydration Salt is indicated in Diarrhea (treatment) and Electrolyte depletion (prophylaxis and treatment)

Composition

Reduced osmolarity: 1/2 liter formula (10.25 gm): Per sachet contains- Sodium chloride 1.30gm Potassium chloride 0.75 gm Tri-sodium citrate dihydrate 1.45 gm Glucose anhydrous 6.75 gm Higher osmolarity: 1/2 liter formula (13.95 gm): Per sachet contains- Sodium chloride 1.75 gm Potassium chloride 0.75 gm Tri-sodium citrate dihydrate 1.45 gm Glucose anhydrous 10 gm Higher osmolarity: 1 liter formula (27.50 gm): Per sachet contains- Sodium chloride 3.5 gm Sodium biocarbonate 2.5 gm Potassium chloride 1.5 gm Glucose anhydrous 20 gm

Theropeutic Class

Oral electrolytes preparations

Pharmacology

Oral rehydration salts are given orally to prevent or treat dehydration due to acute diarrhoea. Essential water and salts are lost in stools and vomiting, and dehydration results when blood volume is decreased because of fluid loss from the extracellular fluid compartment. Preservation of the facilitated glucose-sodium co-transport system in the small-bowel mucosa is the rationale of oral rehydration therapy. Glucose is actively absorbed in the normal intestine and carries sodium with it in about an equimolar ration. Therefore, there is a greater net absorption of an isotonic salt solution with glucose than one without it.Potassium replacement during acute diarrhoea prevents below-normal serum concentrations of potassium, especially in children, in whom stool potassium losses are higher than in adults. Bicarbonates are effective in correcting the metabolic acidosis caused by diarrhoea and dehydration.

Dosage & Administration of ORS 10.25 gm

Children less than 2 years: After each loose stool or vomiting 10 to 20 spoonful (50-100 ml).Children 2 to 10 years: After each loose stool or vomiting 100-200 ml of prepared oral saline.Adult and children above 10 years: After each loose stool or vomiting 200-400 ml of prepared saline.

Interaction of ORS 10.25 gm

There are no known drug interactions and none well documented.

Contraindications

No known contraindications

Side Effects of ORS 10.25 gm

No known side effects

Pregnancy & Lactation

FDA has not yet classified the drug into a specified pregnancy category

Precautions & Warnings

Depressed renal function, severe continuing diarrhoea or other critical fluid losses may need supplementation with parenteral fluids along with oral saline. Solutions containing acetate or gluconate ions should be used with caution, as excess administration may result in metabolic alkalosis. Solutions containing dextrose should be used with caution in patients with known subclinical or overt diabetes mellitus.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

Additional Information

Quantity

25's pack, Piece

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